Produktinformation
Codeine Impurity C is a by-product of the production process of codeine. It is an impurity that has been found in codeine products and can be detected by ultra-high performance liquid chromatography (UPLC). Codeine Impurity C can be identified by its UV detector, which has a flow rate of 1.0 mL/min. UPLC analysis for Codeine Impurity C is performed using a gradient elution with ion-pairing and on-line calibration. The validation parameters are determined at a pH of 3 and a temperature of 25°C. The drug product has to be analysed for Codeine Impurity C before release to ensure that it is within the required limits.
Codeine Impurity C is found in codeine products, as an impurity in the production process. It can be detected by UPLC, which uses a UV detector with flow rate of 1 mL/min, gradient elution with ion pairing, on-line calibration,
