Produktinformation
Name:
Cbz-cyclohexyl-L-glycine
Synonyme:
- (a-S)-a-[[(Phenylmethoxy)carbonyl]amino]cyclohexaneacetic acid(S)-a-[[(phenylmethoxy)carbonyl]amino]cyclohexaneacetic acid
- (2S)-2-Cyclohexyl-2-(phenylmethoxycarbonylamino)acetic acid
- (2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)ethanoic acid
- (S)-2-(((Benzyloxy)carbonyl)amino)-2-cyclohexylaceticacid
- (αS)-α-[[(Phenylmethoxy)carbonyl]amino]cyclohexaneacetic acid
- Cbz-Chg-Oh
- Cbz-Cyclohexyl-L-Glycine
- Cyclohexaneacetic acid, α-[[(phenylmethoxy)carbonyl]amino]-, (S)-
- Cyclohexaneacetic acid, α-[[(phenylmethoxy)carbonyl]amino]-, (αS)-
- N-[(benzyloxy)carbonyl]-N-cyclohexylglycine
- Mehr Synonyme anzeigen
- Z-Chg-Oh
Beschreibung:
Cbz-cyclohexyl-L-glycine is an aminoalcohol that is used as a process development and optimization tool. It is a substrate for proteases, which cleave the peptide bond at the C-terminal end of the molecule. Telaprevir (TPV) is an inhibitor of this enzyme, which inhibits the activity of various viruses, including hepatitis C virus (HCV). TPV is currently undergoing clinical trials for HCV treatment. The TPV molecule can be synthesized by attaching cbz-cyclohexyl-L-glycine to TPV's amide group. This product has shown potential as an antiviral agent against HCV and other viruses.
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Marke:
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Chemische Eigenschaften
Molekulargewicht:
291.34 g/mol
Formel:
C16H21NO4
Reinheit:
Min. 95%
InChl:
InChI=1S/C16H21NO4/c18-15(19)14(13-9-5-2-6-10-13)17-16(20)21-11-12-7-3-1-4-8-12/h1,3-4,7-8,13-14H,2,5-6,9-11H2,(H,17,20)(H,18,19)/t14-/m0/s1
InChI Key:
InChIKey=CUSYTUPJAYLNFQ-AWEZNQCLSA-N
SMILES:
O=C(N[C@H](C(=O)O)C1CCCCC1)OCc1ccccc1
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