a-(4-Chlorophenyl)thio urea

CAS: 3696-23-9

Ref. 3D-FC20353

Produktinformation

• Name: a-(4-Chlorophenyl)thio urea
• Synonyme: 1-(p-Chlorophenyl)-2-thio-ureaN'-(4-Chlorophenyl)carbamimidothioic acidNSC 72217, (4-Chlorophenyl)thiourea, 1-(4-Chlorophenyl)Thiourea, 1-(p-Chlorophenyl)-2-thiourea, 1-(p-Chlorophenyl)thiourea, 4-Chlorophenyl-2-thiourea, Brn 0973258, N-(4-Chlorophenyl)thiourea, N-(p-Chlorophenyl)thiourea, Nsc 72217, N′-(4-Chlorophenyl)carbamimidothioic acid, Thiourea, (4-chlorophenyl)-, Thiourea, (4-chlorophenyl)- (9CI), Thiourea, N-(4-chlorophenyl)-, Thourea, (4-chlorophenyl)- (9CI), Urea, 1-(p-chlorophenyl)-2-thio-, p-Chlorophenylthiourea

Beschreibung

The a-(4-chlorophenyl)thio urea is an efficient method for the synthesis of thiourea derivatives. The method involves chlorinating the corresponding amine with chlorine gas and adding a solution of potassium azide in water to give the 4-chlorophenylthio urea. This reaction is catalyzed by hydrochloric acid or other strong mineral acids. The product is purified by recrystallization and characterized by melting point, IR spectroscopy, elemental analysis, and NMR spectroscopy. The compounds are effective inhibitors of melanogenesis and have potent inhibitory activity against ABCA1.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 186.66 g/mol
• Formel: C₇H₇ClN₂S
• Reinheit: Min. 95%
• InChl: InChI=1S/C7H7ClN2S/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)
• InChI Key: InChIKey=XVEFWRUIYOXUGG-UHFFFAOYSA-N
• SMILES: NC(=S)Nc1ccc(Cl)cc1