1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester

CAS: 112811-71-9

Ref. 3D-FC20734

Produktinformation

• Name: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester
• Synonyme: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid ethyl, 1-Cyclopropyl-6,7-Difluoro-1,4-Dihydro-8-Methoxy-4-Oxo-3-Quinoline Carboxylic Acid Ethyl Ester, Ethyl 1-Cyclopropyl-6,7-Difluoro-8-Methoxy-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate, Ethyl 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-Quinolinecarboxylate, Gatifloxacin macrolide, Gatifloxacin intermediate, Ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylate
• CAS: 112811-71-9

Beschreibung

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester (1CPD) is an industrial chemical that is synthesized by the reaction of thiomorpholine with hydrochloric acid in acetonitrile. 1CPD has been shown to have potent antibacterial activity against a number of bacteria. It was also found to be effective against methicillin resistant Staphylococcus aureus and Mycobacterium tuberculosis. 1CPD inhibits bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 323.29 g/mol
• Formel: C₁₆H₁₅F₂NO₄
• Reinheit: Min. 95%
• InChl: InChI=1S/C16H15F2NO4/c1-3-23-16(21)10-7-19(8-4-5-8)13-9(14(10)20)6-11(17)12(18)15(13)22-2/h6-8H,3-5H2,1-2H3
• InChI Key: InChIKey=XPAOPAPDCRLMTR-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cn(C2CC2)c2c(OC)c(F)c(F)cc2c1=O