7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

CAS: 2886-65-9

Ref. 3D-FC26451

Produktinformation

• Name: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• Synonyme: 5-(2-Fluorophenyl)-1,3-dihydro-7-chloro-2H-1,4-benzodiazepin-2-oneNorfludiazepamDesalkylflurazepam, 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-, 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-fluorophenyl)-1,3-dihydro-, 5-(2-Fluorophenyl)-7-Chloro-1,4-Benzodiazepin-2-One, 7-Chloro-1,3-dihydro-5-(2′-fluorophenyl)-2H-1,4-benzodiazapin-2-one, 7-Chloro-5-(2-Fluoro-Phenyl)-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One, 7-Chloro-5-(o-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one, 7-Chloro-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, Cm 7116, Dealkylflurazepam, Desalkylflurazepam, Descarbethoxyloflazepate, N-1-Desalkylflurazepam, N-Desalkyl-2-oxoquazepam, N-Desalkylflutoprazepam, Norflurazepam, Norflutoprazepam, Ro 5-3367, Sch 17514
• CAS: 2886-65-9

Beschreibung

7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one is a GABA receptor antagonist that is used in the treatment of anxiety. It is an analogue of cinolazepam, which has been shown to inhibit the binding of gamma aminobutyric acid (GABA) to its receptors in human serum and urine samples. Cinolazepam was found to be more potent than 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4 benzodiazepin 2 one in blocking the binding of GABA to its receptor. This drug has also been tested on geriatric patients with high levels of anxiety and found to be well tolerated.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 288.7 g/mol
• Formel: C₁₅H₁₀ClFN₂O
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Powder
• InChl: InChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
• InChI Key: InChIKey=UVCOILFBWYKHHB-UHFFFAOYSA-N
• SMILES: O=C1CN=C(c2ccccc2F)c2cc(Cl)ccc2N1