Calpain Inhibitor II

CAS: 110115-07-6

Ref. 3D-FC29615

Produktinformation

• Name: Calpain Inhibitor II
• Synonyme: <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[1-formyl-3-(methylthio)propyl]-, (S)-, Ac-Leu-Leu-Met-aldehyde, Ac-Leu-Leu-methioninal, Allm, Calp II, N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-<smallcap>L</span>-leucinamide, N-Acetyl-L-leucyl-L-leucyl-L-methioninal, N-acetyl-L-leucyl-N-[(1R)-1-formyl-3-(methylsulfanyl)propyl]-L-leucinamide, N-acetyl-L-leucyl-N-[(2S)-4-(methylsulfanyl)-1-oxobutan-2-yl]-L-leucinamide, N-acetylleucyl-N-[4-(methylsulfanyl)-1-oxobutan-2-yl]leucinamide, Suam 312, L-Leucinamide, N-acetyl-L-leucyl-N-[1-formyl-3-(methylthio)propyl]-, (S)-, N-Acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide, L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-

Beschreibung

Inhibitor of calpain, a calcium-dependent cysteine protease which is implicated in the apoptosis as well as in synaptic plasticity, where it was seen to block long-term potentiation. Calpain inhibitor II has also antiviral properties as it was shown to inhibit the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.97 μM.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 401.57 g/mol
• Formel: C₁₉H₃₅N₃O₄S
• Reinheit: Min. 95%
• Farbe/Form: Powder