4-Chloro Kynurenine

CAS: 75802-84-5

Ref. 3D-FC34922

Produktinformation

• Name: 4-Chloro Kynurenine
• Synonyme: 2-Amino-4-(2-Amino-4-Chlorophenyl)-4-Oxobutanoic Acid

Beschreibung

4-Chloro Kynurenine is an aminotransferase activator that has been shown to produce antidepressant responses in animals. It is also a prodrug of rapamycin, which acts as an immunosuppressant and prevents the uptake of glutamate. 4-Chloro Kynurenine is used for the treatment of treatment-resistant depression. It inhibits glycogen synthase kinase-3 (GSK-3) and enhances the uptake of glutamate by organic anion transporters (OATs). This inhibition increases neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). These findings suggest that 4-chloro kynurenine may be a novel drug for the treatment of depression.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 242.66 g/mol
• Formel: C₁₀H₁₁ClN₂O₃
• Reinheit: Min. 95%
• Farbe/Form: Off-White Powder
• InChl: InChI=1S/C10H11ClN2O3/c11-5-1-2-6(7(12)3-5)9(14)4-8(13)10(15)16/h1-3,8H,4,12-13H2,(H,15,16)
• InChI Key: InChIKey=HQLHZNDJQSRKDT-UHFFFAOYSA-N
• SMILES: Nc1cc(Cl)ccc1C(=O)CC(N)C(=O)O