N-Cyclohexyl-N'-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate

CAS: 2491-17-0

Ref. 3D-FC55888

Produktinformation

• Name: N-Cyclohexyl-N'-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate
• Synonyme: Morpho-CDICME-carbodiimide

Beschreibung

N-Cyclohexyl-N'-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate, also known as CMC, CMCT, Morpho-CDI and CME-carbodiimide, is a reagent widely used in the detection of post-transcriptional modifications on nucleosides in RNA. RNA chemical probing is a powerful technology used to address numerous biological questions. The main application of CMC is the chemical modification of pseudouridine in RNA, in order to detect it and quantify it using analytical techniques such as primer extension or MALDI. Pseudouridine is the most abundant modification occurring in cellular RNA, and is responsible for the increased rigidity of the phosphate backbone and base stacking, impacting important RNA interactions.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 423.57 g/mol
• Formel: C₂₁H₃₃N₃O₄S
• Reinheit: Min. 94 Area-%
• Farbe/Form: White Off-White Powder