Conessine

CAS: 546-06-5

Ref. 3D-FC57645

Produktinformation

• Name: Conessine
• Synonyme: (3-beta)-N,N-Dimethylcon-5-enin-3-amine, (3alpha,8xi,9xi,10alpha,14xi,17beta)-N,N-dimethylcon-5-enin-3-amine, (3beta,8xi,9xi,14xi,17xi)-N,N-dimethylcon-5-enin-3-amine, (3β)-N,N-Dimethylcon-5-enin-3-amine, 1H-Naphth[2′,1′:4,5]indeno[1,7a-c]pyrrole, con-5-enin-3-amine deriv., 3beta-(Dimethylamino)con-5-ene, 3beta-(Dimethylamino)con-5-enine, Brn 4702160, Con-5-enin-3-amine, N,N-dimethyl-, (3beta)- (9CI), Con-5-enin-3-amine, N,N-dimethyl-, (3β)-, Con-5-enine, 3beta-(dimethylamino)- (8CI), Con-5-enine, 3β-(dimethylamino)-, Conesina, Conesina [INN-Spanish], Conessin, Conessine [INN], Conessinum, Conessinum [INN-Latin], Conkurchine, N,18-dihydrotrimethyl-, Conkurchine, N,18-dihydrotrimethyl- (7CI), Konessin, N,N-dimethylcon-5-enin-3-amine, Neriine, Nsc 119994, N′,18-Dihydro-N,N,N′-trimethylconkurchine, Roquessine, Unii-Ez38J9Bbdf, Wrightine
• CAS: 546-06-5

Beschreibung

Conessine is a natural compound that inhibits the ubiquitin ligase, which is an enzyme involved in protein degradation. It has been shown to have inhibitory properties on bone cancer and melanogenesis. Conessine has also been found to be active against infectious diseases such as tuberculosis and malaria. The inhibitory effects of conessine are mediated by its ability to bind to the substrate-binding site of the ubiquitin ligase. This binding prevents the ubiquitin ligase from binding with other proteins and then initiating their degradation. Conessine also binds to steroidal alkaloids and multidrug efflux pumps, which may account for its pharmacokinetic properties.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 356.59 g/mol
• Formel: C₂₄H₄₀N₂
• Reinheit: Min. 95%
• Farbe/Form: White Powder
• InChl: InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1
• InChI Key: InChIKey=GPLGAQQQNWMVMM-MYAJQUOBSA-N
• SMILES: C[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](N(C)C)CC[C@]5(C)[C@H]4CC[C@]23CN1C