1-(Pyridin-4-yl)-N-(thiophen-2-ylmethyl)methanamine

CAS: 680185-81-3

Ref. 3D-FCB18581

Produktinformation

• Name: 1-(Pyridin-4-yl)-N-(thiophen-2-ylmethyl)methanamine
• Synonyme: 4-Pyridinemethanamine, N-(2-thienylmethyl)-, N-(2-Thienylmethyl)-4-pyridinemethanamine, [(Pyridin-4-yl)methyl][(thiophen-2-yl)methyl]amine, 1-Pyridin-4-yl-N-(thiophen-2-ylmethyl)methanamine, (Pyridin-4-ylmethyl)(thiophen-2-ylmethyl)amine

Beschreibung

THP-1 cells were transfected with pcDNA3.1 plasmid encoding wnt/β-catenin pathway reporter and co-cultured with a mouse neural stem cell line, Cerebellar Granule Cell Line (CGC). The THP-1 cells were stimulated with 1-(pyridin-4-yl)-N-(thiophen-2-ylmethyl)methanamine (PTM), a Wnt ligand that is known to induce follicle development in the ovary, and then treated with the proteasome inhibitor MG132. The data showed that PTM induced ectopic expression of β-catenin in CGCs. This suggests that PTM may be a useful therapeutic tool for the treatment of follicle development disorders in humans due to its ability to induce β-catenin expression.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 204.29 g/mol
• Formel: C₁₁H₁₂N₂S
• Reinheit: Min. 95%