2,4-Dihydroxypyrimidine-5-carboxylic acid anhydrous

CAS: 23945-44-0

Ref. 3D-FD08255

Produktinformation

• Name: 2,4-Dihydroxypyrimidine-5-carboxylic acid anhydrous
• Synonyme: Uracil-5-carboxylic acidIsoorotic acidUracil 5-carboxylic acid, 1,2,3,4-Tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid, 2,4-Dihydroxy-5-pyrimidinecarboxylic acid, 2,4-Dihydroxypyrimidine-5-Carboxylic acid hydrate, 2,4-Dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, 2,4-Dioxo-1H-pyrimidine-5-carboxylic acid, 5-Carboxy-2,4-dihydroxypyrimidine, 5-Carboxyuracil, 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, 5-Pyrimidinecarboxylic acid, 2,4-dihydroxy-, 5-Uracilcarboxylic acid, Isoorotic acid, NSC 1589, NSC 79561

Beschreibung

2,4-Dihydroxypyrimidine-5-carboxylic acid anhydrous (2,4DPA) is a metabolite of the drug 2,4-diaminopyrimidine. It inhibits protein synthesis in cells through hydrogen bonding interactions with dna duplexes and has been shown to be toxic to bacteria by inhibiting fatty acid biosynthesis. 2,4DPA is used as a standard in biological assays to measure uptake and light exposure. The analytical method for measuring 2,4DPA relies on hydrochloric acid (HCl) as a solvent that converts the material into its dimethyl ester derivative. This derivative can be quantified by gas chromatography/mass spectrometry (GCMS).

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 156.1 g/mol
• Formel: C₅H₄N₂O₄
• Reinheit: Min. 94.0 Area-%
• Farbe/Form: White Off-White Powder
• InChl: InChI=1S/C5H4N2O4/c8-3-2(4(9)10)1-6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)
• InChI Key: InChIKey=ZXYAAVBXHKCJJB-UHFFFAOYSA-N
• SMILES: O=C(O)c1c[nH]c(=O)[nH]c1=O