9-Deazaguanine

CAS: 65996-58-9

Ref. 3D-FD09249

Produktinformation

• Name: 9-Deazaguanine
• Synonyme: 2-Amino-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-5H-pyrrolo[3,2-d]pyrimidin-4-ol, 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-3,5-dihydro-, 5H-pyrrolo[3,2-d]pyrimidin-4-ol, 2-amino-, 2-Amino-3,5-Dihydro-Pyrrolo[3,2-D]Pyrimidin-4-One

Beschreibung

9-Deazaguanine is an analog of guanine, which has inhibitory properties. It reacts with the hydrogen bond of the enzyme and prevents its reaction with a substrate. 9-Deazaguanine binds to the target enzymes trifluoroacetic acid (TFA) and hydrogen bond interactions with water molecules. The reaction mechanism is based on the competitive inhibition of TFA, which is an important enzyme in DNA synthesis. 9-Deazaguanine inhibits the growth of k562 cells by inhibiting protein synthesis at specific sites in the ribosome. 9-Deazaguanine also shows inhibitory properties against autoimmune diseases and infectious diseases because it inhibits immune system reactions that are mediated by antibodies and T cells.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 150.14 g/mol
• Formel: C₆H₆N₄O
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C6H6N4O/c7-6-9-3-1-2-8-4(3)5(11)10-6/h1-2,8H,(H3,7,9,10,11)
• InChI Key: InChIKey=FFYPRJYSJODFFD-UHFFFAOYSA-N
• SMILES: Nc1nc2cc[nH]c2c(=O)[nH]1