Produktinformation
Name:
DCC-2618
Beschreibung:
DCC-2618 is a zirconium oxide-based compound that binds to the ATP binding site of the Bcr-Abl kinase domain. The compound inhibits the phosphorylation of tyrosine residues in proteins on which it has been targeted, leading to cell death. DCC-2618 is an orally bioavailable drug that is well tolerated by patients. It is a potent inhibitor of myeloproliferative disorders and cancer cells with constitutive activation of the Bcr-Abl kinase domain. Inhibition of this kinase leads to cell cycle arrest, apoptosis, and suppression of tumor growth in mice.
Hinweis:
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Marke:
Biosynth
Langzeitlagerung:
Hinweise:
Chemische Eigenschaften
Molekulargewicht:
489.47 g/mol
Formel:
C26H21F2N5O3
Reinheit:
Min. 95%
MDL:
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