Dansyl-Glu-Gly-Arg-chloromethylketone

CAS: 69024-84-6

Ref. 3D-FD111116

Produktinformation

• Name: Dansyl-Glu-Gly-Arg-chloromethylketone
• Synonyme: Glycinamide,N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-a-glutamyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-(9CI), Glycinamide, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-a-glutamyl-N-[4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-,(S)-, Dansylglutamyl-Glycyl-Arginine Chloromethyl Ketone
• CAS: 69024-84-6

Beschreibung

Dansyl-Glu-Gly-Arg-chloromethylketone is a fluorescent substrate for epidermal growth factor (EGF). It has been shown to inhibit the proteolytic activity of EGF. This inhibition is due to the binding of Dansyl-Glu-Gly-Arg-chloromethylketone to calcium and its inhibitory properties on EGF. The flow system used in this experiment was activated with a monoclonal antibody, which binds to the cytosolic calcium and activates the enzyme. The kinetic data obtained from this experiment showed that the rate of EGF hydrolysis by Dansyl-Glu-Gly-Arg-chloromethylketone was proportional to the concentration of calcium in the cytosol.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 626.13 g/mol
• Formel: C₂₆H₃₆ClN₇O₇S
• Reinheit: Min. 95%