2-(Dimethylamino)nicotinonitrile

CAS: 60138-76-3

Ref. 3D-FD121666

Produktinformation

• Name: 2-(Dimethylamino)nicotinonitrile
• Synonyme: 3-pyridinecarbonitrile, 2-(dimethylamino)-, 3-Pyridinecarbonitrile, 2-(Dimethylamino)-
• CAS: 60138-76-3

Beschreibung

2-(Dimethylamino)nicotinonitrile is a precursor for the synthesis of aminopyridines. It is prepared by diazotizing 2-amino-5-nitropyridine with sodium nitrite in concentrated hydrochloric acid, followed by addition of dimethylformamide and trifluoromethanesulfonic acid. The reaction yields 2-(dimethylamino)nicotinonitrile, as well as other products including 2-methylpiperidine and 4-methylpiperidine. This process can be improved by using microwaves or a catalyst such as trifluoromethanesulfonic anhydride or trifluoroacetic anhydride.
2-(Dimethylamino)nicotinonitrile is used to synthesize aminopyridines, which are intermediates in the production of various medications such as antibiotics and cancer drugs.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 147.18 g/mol
• Formel: C₈H₉N₃
• Reinheit: Min. 95%