Produktinformation
- Methanesulfonamide,N-[4-[2-[methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-,N-oxide
- Uk 116856
Dofetilide N-oxide is a proarrhythmic drug that belongs to the class of flecainide. It has been shown in pharmacology studies to prolong the duration of atrial ventricular and atrial fibrillation in humans. Dofetilide N-oxide also has an activating effect on cardiac cells and may be used for the treatment of ventricular arrhythmias. The clinical response can be blocked by other drugs such as beta blockers, which are used to treat cardiovascular diseases. Dofetilide N-oxide has a constant plasma concentration profile, meaning that its concentration does not change with time or body weight.