Azaserine

CAS: 115-02-6

Ref. 3D-FD145614

Produktinformation

• Name: Azaserine
• Synonyme: O-(2-11Diazoacetyl)-L-serine, (2S)-2-Amino-3-[(2-diazoacetyl)oxy]propanoic acid, (E)-1-(2-amino-2-carboxyethoxy)-2-diazonioethenolate, (E)-1-[(2S)-2-amino-2-carboxyethoxy]-2-diazonioethenolate, (S)-2-Amino-3-(2-diazoacetoxy)propanoic acid, 1-(2-Amino-2-Carboxyethoxy)-2-Diazonioethenolate, <span class="text-smallcaps">L</span>-Azaserine, <span class="text-smallcaps">L</span>-Serine, O-(2-diazoacetyl)-, <span class="text-smallcaps">L</span>-Serine, diazoacetate (ester), Azaserin, Ci 337, Cn 15757, NSC 742, O-(2-Diazoacetyl)-<span class="text-smallcaps">L</span>-serine, O-(diazen-1-iumylideneacetyl)serine, O-(diazoacetyl)serine, O-Diazoacetyl-<span class="text-smallcaps">L</span>-serine, P 165, Serine, diazoacetate (ester), <span class="text-smallcaps">L</span>-

Beschreibung

Glutamine analogue and antagonist of glutamine-dependent amidotransferases, with antibiotic and antifungal properties. Inhibits purine biosynthesis, FGAM synthetase and glucosamine-6-phosphate isomerase that contributes to its antineoplastic property. Azaserine can also act as a carcinogen, by inducing DNA carboxymethylation. Protects endothelial cells from inflammation under hyperglycemic conditions, via antioxidant mechanisms, independent of hexosamine biosynthetic pathway.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 173.13 g/mol
• Formel: C₅H₇N₃O₄
• Reinheit: Min. 98 Area-%
• Farbe/Form: Slightly Yellow Powder