1,2-Dimethylindole-3-carboxylicacid

CAS: 20357-15-7

Ref. 3D-FD149422

Produktinformation

• Name: 1,2-Dimethylindole-3-carboxylicacid
• Synonyme: 1,2-Dimethyl-1H-indole-3-carboxylic acid, 1,2-dimethyl-1H-indole-3-carboxylate, 1H-Indole-3-carboxylic acid, 1,2-dimethyl-, Indole-3-carboxylic acid, 1,2-dimethyl-

Beschreibung

1,2-Dimethylindole-3-carboxylicacid is a synthetic compound that has been extensively screened for antiviral activity and found to be effective against hepatitis C virus. It inhibits HMG-CoA reductase by binding to the active site of the enzyme, inhibiting its ability to catalyze the conversion of HMG-CoA to mevalonate. This leads to reduced synthesis of sterols, which are necessary for lipid biosynthesis and cell membrane biogenesis. 1,2-Dimethylindole-3-carboxylicacid is stereoselectively active at the (R) enantiomer. The drug also has hepatoselective effects in animal models.
1,2-Dimethylindole-3-carboxylicacid is a linker analog of pyrazoles that have been shown to have antiinflammatory properties in human cells grown in culture. Efflux of this drug from cells may be due to increased

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 189.21 g/mol
• Formel: C₁₁H₁₁NO₂
• Reinheit: Min. 95%