DEPBT

CAS: 165534-43-0

Ref. 3D-FD15562

Produktinformation

• Name: DEPBT
• Synonyme: 3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one
• Marke: Biosynth
• Beschreibung: DEPBT is an organophosphorous coupling reagent used in peptide chemistry. DEPBT is efficient in the synthesis of linear, cyclic and sterically hindered peptides, in solution and solid phase synthesis, achieving high yields with fast kinetics and remarkable retention of configuration. DEPBT can be easily synthesised, is a crystalline phosphate stable for months and shows often better performances than the commonly used phosphonium and uronium salts. Notably, in presence of DEPBT it is not necessary to protect the hydroxyl group in the amino acids (such as tyrosine, serine, and threonine) and the imidazole group of histidine. Therefore, DEPBT can be employed in the synthesis of amino alcohols and N-glycopeptides. DEPBT finds application in the synthesis of numerous bioactive peptides and complex natural products.

Chemische Eigenschaften

• Molekulargewicht: 299.22 g/mol
• Formel: C₁₁H₁₄N₃O₅P
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C11H14N3O5P/c1-3-17-20(16,18-4-2)19-14-11(15)9-7-5-6-8-10(9)12-13-14/h5-8H,3-4H2,1-2H3
• InChI Key: InChIKey=AJDPNPAGZMZOMN-UHFFFAOYSA-N
• SMILES: CCOP(=O)(OCC)On1nnc2ccccc2c1=O