Donepezil hydrochloride monohydrate
CAS: 884740-09-4
Ref. 3D-FD158867
| 2mg | Ausgelaufen | ||
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Produktinformation
Donepezil is a natural compound that has been shown to have clinical relevance in the treatment of Alzheimer's disease. Donepezil inhibits acetylcholinesterase and thus increases the amount of acetylcholine available at synapses. This drug has been shown to stimulate locomotor activity and to inhibit oxidative injury in animal studies. Donepezil also binds to a number of different receptor types, including cholinergic receptors and microglial cells. It has been found to be polymorphic with respect to its hydroxyl group, which can produce four different monohydroxy metabolites: donepezil hydroxylamine (DHA), donepezil hydroxylamine sulfate (DHAS), donepezil hydroxylamine glucuronide (DHAG), and donepezil hydroxylamine sulfamate (DHS). These metabolites have different pharmacological properties.
