Dapsone

CAS: 80-08-0

Ref. 3D-FD20798

Produktinformation

• Name: Dapsone
• Synonyme: DADPSDDSAvlosulfonCroysulfoneDiphenasoneDisuloneDumitoneEporalSulphadione,4,4'-sulfonylbisbenzeneamine
• Marke: Biosynth
• Beschreibung: Dapsone is a nonsteroidal anti-inflammatory drug that is used to treat various types of infectious diseases and skin disorders. It acts by blocking the synthesis of dihydrofolic acid, which leads to inhibition of bacterial growth. Dapsone inhibits the activity of monoethyl ether reductase (NADH) in human polymorphonuclear leukocytes, which slows the production of hydrogen peroxide and prevents oxidative damage to cellular components. It has been shown to be effective against both erythema multiforme and chronic dermatitis herpetiformis with minimal side effects. The use of dapsone may be helpful in diagnosis as it can inhibit polymerase chain reactions that are specific for squamous cells. There are also reports that dapsone may affect intestinal motility and cause bowel disease.

Chemische Eigenschaften

• Molekulargewicht: 248.3 g/mol
• Formel: C₁₂H₁₂N₂O₂S
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Powder
• InChl: InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
• InChI Key: InChIKey=MQJKPEGWNLWLTK-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1