Deshydroxy bicalutamide

CAS: 906008-94-4

Ref. 3D-FD21200

Produktinformation

• Name: Deshydroxy bicalutamide
• Synonyme: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-methylpropanamide
• Marke: Biosynth
• Beschreibung: Deshydroxy bicalutamide is a ligand that has been synthesized to bind to the androgen receptor. It is an antagonist of the androgen receptor. Deshydroxy bicalutamide has been shown to inhibit cancer cell growth in prostate cancer cell lines, which is due to its ability to bind and block the ligand-binding domain of the androgen receptor. Molecular modelling has shown that deshydroxy bicalutamide binds in the hydroxyl group region of the binding site, which blocks it from binding with other ligands such as testosterone. This may lead to decreased levels of testosterone in males, leading to decreased levels of androgens in prostate cancer cells.

Chemische Eigenschaften

• Molekulargewicht: 414.38 g/mol
• Formel: C₁₈H₁₄F₄N₂O₃S
• Reinheit: Min. 95%