O-Desmethyl carvedilol
CAS: 72956-44-6
Ref. 3D-FD21247
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Produktinformation
Name:
O-Desmethyl carvedilol
Synonyme:
- 2-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]phenolBM 14242Desmethylcarvedilol
- Phenol, 2-(2-((3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)amino)ethoxy)-
Beschreibung:
O-Desmethyl Carvedilol is a metabolite of Carvedilol, which is an effective oral anti-hypertensive agent. O-Desmethyl Carvedilol is a potent inhibitor of the hepatic cytochrome P450 system and inhibits the activity of human liver microsomes at concentrations of 10 μM. The LC-MS/MS method for measuring O-Desmethyl Carvedilol in urine samples has been validated and found to be accurate and precise. Clinical studies have shown that carvedilol has a profile of lipid lowering, vasodilation, and anti-ischaemic effects with relatively few side effects. Studies have also shown that carvedilol is metabolized by the liver into active metabolites such as O-desmethyl carvadiol (ODC).
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
392.45 g/mol
Formel:
C23H24N2O4
Reinheit:
Min. 95%
InChl:
InChI=1S/C23H24N2O4/c26-16(14-24-12-13-28-21-10-4-3-9-20(21)27)15-29-22-11-5-8-19-23(22)17-6-1-2-7-18(17)25-19/h1-11,16,24-27H,12-15H2
InChI Key:
InChIKey=XAUKPPPYYOKVQJ-UHFFFAOYSA-N
SMILES:
Oc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12
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