3',4'-Dihydroxyetoposide

CAS: 100007-54-3

Ref. 3D-FD21267

Produktinformation

• Name: 3',4'-Dihydroxyetoposide
• Synonyme: 3',4'-Dihydroxy-VP 16-213, Dhvp-16-213, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5-(3,4-dihydroxy-5-methoxyphenyl)-9-((4,6-O-ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-, (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-, (5S,5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside

Beschreibung

3',4'-Dihydroxyetoposide is an anti-cancer agent that belongs to the group of epipodophyllotoxins. It inhibits DNA synthesis and cell division by binding to topoisomerase II, leading to DNA breakage and the formation of single-stranded breaks. 3',4'-Dihydroxyetoposide has been shown to be safe for use in children with leukemia, although it is not active against cells without a nucleus, such as erythrocytes. This drug also has significant inhibition of human cytochrome P450 3A4 (CYP3A4) and human liver microsomes.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 574.53 g/mol
• Formel: C₂₈H₃₀O₁₃
• Reinheit: Min. 95%