6',7'-Dihydroxy bergamottin

CAS: 145414-76-2

Ref. 3D-FD22049

Produktinformation

• Name: 6',7'-Dihydroxy bergamottin
• Synonyme: 4-[[(2E)-6,7-Dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one, 4-{[(2E)-6,7-dihydroxy-3,7-dimethyloct-2-en-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one, 6,7-Dihydroxybergagamottin, 6′,7′-Dihydroxybergamottin, 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[(6,7-dihydroxy-3,7-dimethyl-2-octenyl)oxy]-, (E)-, 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-, 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octenyl]oxy]-, Dihydroxybergamottin

Beschreibung

Bergamottin is a naturally occurring flavonoid that is found in grapefruit and other citrus fruit. It has been shown to inhibit the activity of the P-glycoprotein (P-gp) transporter in human cells, which may lead to drug interactions. A number of analytical methods have been developed for the determination of bergamottin in biological samples such as humans, rat liver microsomes, and natural compounds. Bergamottin has been shown to be a potent inhibitor of cytochrome P450 enzymes and can inhibit skin cancer development in mice by inhibiting the growth of human keratinocytes (HK-2 cells). Bergamottin also inhibits tumorigenesis in mice by decreasing cell proliferation and inducing apoptosis in hk-2 cells.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 372.41 g/mol
• Formel: C₂₁H₂₄O₆
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C21H24O6/c1-13(4-6-18(22)21(2,3)24)8-10-26-20-14-5-7-19(23)27-17(14)12-16-15(20)9-11-25-16/h5,7-9,11-12,18,22,24H,4,6,10H2,1-3H3/b13-8+
• InChI Key: InChIKey=IXZUPBUEKFXTSD-MDWZMJQESA-N
• SMILES: C/C(=C\COc1c2ccoc2cc2oc(=O)ccc12)CCC(O)C(C)(C)O