7a,12a-Dihydroxycholest-4-en-3-one
CAS: 1254-03-1
Ref. 3D-FD22108
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Produktinformation
- (7a,12a)-7,12-Dihydroxycholest-4-en-3-oneCholest-4-ene-7a,12a-diol-3-one
- (7Alpha,12Alpha)-7,12-Dihydroxycholest-4-En-3-One
- (7a,12a)-7,12-Dihydroxycholest-4-en-3-one
- 7a,12a-Dihydroxycholest-4-en-3one
- 7α,12α-Dihydroxycholest-4-en-3-one
- Cholest-4-en-3-one, 7,12-dihydroxy-, (7α,12α)-
- Cholest-4-en-3-one, 7α,12α-dihydroxy-
- Cholest-4-ene-7a,12a-diol-3-one
7a,12a-Dihydroxylcholest-4-en-3-one is a structural analog of 7α,12α-dihydroxycholesterol. It has been studied for its catalytic mechanism and cavity. It is formed from the reaction of glutamate with cholesterol in a homogenate. The enzyme responsible for this biosynthesis is HMG CoA reductase, which converts 3 hydroxymethylglutaryl coenzyme A to mevalonate. Biochemical studies have shown that 7α,12α-dihydroxylcholest-4-en-3-one is metabolized by the liver into bile acids and excreted in the urine. This compound has also been shown to be an antiinflammatory agent due to its ability to inhibit prostaglandin synthesis and reduce inflammation.
Chemische Eigenschaften
Technische Anfrage zu: 3D-FD22108 7a,12a-Dihydroxycholest-4-en-3-one
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