4,5-Dibromothiophene-2-carboxylic acid

CAS: 6324-10-3

Ref. 3D-FD36258

Produktinformation

• Name: 4,5-Dibromothiophene-2-carboxylic acid
• Synonyme: 2,3-Dibromo-5-thiophenecarboxylic acid, 2-Thiophenecarboxylic acid, 4,5-dibromo-, 4,5-Dibromo-2-thiophenecarboxylic acid, 4,5-Dibromothenoic acid, NSC 30091
• CAS: 6324-10-3

Beschreibung

4,5-Dibromothiophene-2-carboxylic acid is a chiral compound that has been shown to be effective at inhibiting urokinase-type plasminogen activator (uPA) with an IC50 of about 10 nM. This inhibition is due to the postulated ability of 4,5-dibromothiophene-2-carboxylic acid to bind to the active site of uPA. The binding of 4,5-dibromothiophene-2-carboxylic acid to uPA leads to a decrease in the catalytic activity of uPA and inhibits the formation of plasmin. This decreases the production of neurokinin, which is involved in pain sensation. 4,5-Dibromothiophene-2-carboxylic acid also has pharmacokinetic properties that are similar to those seen in other pyrazole derivatives. It is selectively bound by

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 285.94 g/mol
• Formel: C₅H₂Br₂O₂S
• Reinheit: Min. 95%