(R)-(-)-N-(3,5-Dinitrobenzoyl)-a-phenylglycine

CAS: 74927-72-3

Ref. 3D-FD39706

Produktinformation

• Name: (R)-(-)-N-(3,5-Dinitrobenzoyl)-a-phenylglycine
• Synonyme: (2R)-[(3,5-Dinitrobenzoyl)amino](phenyl)acetic acid, benzeneacetic acid, alpha-[(3,5-dinitrobenzoyl)amino]-, (alphaR)-, (2R)-{[(3,5-dinitrophenyl)carbonyl]amino}(phenyl)ethanoate, (R)-(− )-N-(3,5-Dinitrobenzoyl)-α-phenylglycine

Beschreibung

(R)-(-)-N-(3,5-Dinitrobenzoyl)-a-phenylglycine ((R)-DBBG) is a chiral molecule that is used as an anthelmintic drug. It is a derivative of the amino acid glycine and has been shown to inhibit angiogenesis in cancerous tumors. (R)-DBBG inhibits fatty acid synthesis by binding to the acyl carrier protein and inhibiting the conversion of acetate to malonyl coenzyme A. This inhibition leads to a depletion of long-chain fatty acids, which can be detected by chromatography. The enantiomers have been shown to have different effects on rat liver microsomes, with one enantiomer being more potent than the other. The kinetic studies show that the amines react with R-DBBG and form an intermediate with a reactive α1-acid glycoprotein, which subsequently reacts with hydrogen peroxide and forms a reactive intermediate that decom

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 345.26 g/mol
• Formel: C₁₅H₁₁N₃O₇
• Reinheit: Min. 95%