3,4-Dihydro-2(1H)-Quinolinone

CAS: 553-03-7

Ref. 3D-FD40543

Produktinformation

• Name: 3,4-Dihydro-2(1H)-Quinolinone
• Synonyme: 1,2,3,4-Tetrahydroquinolin-2-One, 3,4-dihydroquinolin-2(1H)-one, 3,4-dihydro-1H-quinolin-2-one

Beschreibung

3,4-Dihydro-2(1H)-quinolinone is a potent inhibitor of dopamine β-hydroxylase and is used as a model system to study the pharmacokinetic properties of carbostyril. It has been shown that 3,4-dihydro-2(1H)-quinolinone binds to the chloride ion in the active site of dopamine β-hydroxylase. This binding prevents the formation of a complex with the enzyme's substrate, which is required for catalysis. 3,4-Dihydro-2(1H)-quinolinone also interacts with the alkynyl group on dopamine and competitively inhibits its metabolism by monoamine oxidase (MAO).

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 147.17 g/mol
• Formel: C₉H₉NO
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C9H9NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-4H,5-6H2,(H,10,11)
• InChI Key: InChIKey=TZOYXRMEFDYWDQ-UHFFFAOYSA-N
• SMILES: O=C1CCc2ccccc2N1