2,2-Difluoro-5-aminobenzodioxole

CAS: 1544-85-0

Ref. 3D-FD42943

Produktinformation

• Name: 2,2-Difluoro-5-aminobenzodioxole
• Synonyme: 2,2-Difluoro-5-amino-1,3-benzodioxole, 2,2-Difluorobenzo[D][1,3]Dioxol-5-Amine, 1-(Difluoromethoxy)-4-Nitrobenzene, 2,2-Difluoro-5-aminobenzo[d][1,3]dioxole

Beschreibung

2,2-Difluoro-5-aminobenzodioxole is a radiopharmaceutical that is used to image β-amyloid plaques in the brain of patients with Alzheimer's disease. This compound binds to β-amyloid and emits positrons, which are detected by a gamma camera. 2,2-Difluoro-5-aminobenzodioxole was synthesized from benzoic acid and alkylation with difluoromethane. This molecule has been shown to inhibit casein kinase I and II, which are involved in the phosphorylation of casein and the degradation of amyloid precursor protein (APP).

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 173.12 g/mol
• Formel: C₇H₅F₂NO₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C7H5F2NO2/c8-7(9)11-5-2-1-4(10)3-6(5)12-7/h1-3H,10H2
• InChI Key: InChIKey=CVYQRDKVWVBOFP-UHFFFAOYSA-N
• SMILES: Nc1ccc2c(c1)OC(F)(F)O2