Diethyl (1,3-Dithian-2-yl)phosphonate
CAS: 62999-73-9
Ref. 3D-FD59862
1g | Ausgelaufen | ||
2g | Ausgelaufen | ||
5g | Ausgelaufen | ||
10g | Ausgelaufen | ||
25g | Ausgelaufen |
Produktinformation
- (1,3-Dithian-2-yl)phosphonic Acid Diethyl Ester
Diethyl (1,3-Dithian-2-yl)phosphonate is a podophyllotoxin analog that has been shown to have enhanced antitumor activity against murine leukemia and L1210 murine leukemia. It is an ancillary in the asymmetric synthesis of β-amino acid derivatives, benzylidene acetals, and podophyllotoxin analogues. The l1210 murine leukemia cells are sensitive to diethyl (1,3-dithian-2-yl)phosphonate because it can form covalent bonds with DNA by electron donation. These compounds are also found to be cytotoxic against other tumor cells including human breast cancer cells.