Diethyl (1,3-Dithian-2-yl)phosphonate

Ref. 3D-FD59862

Produktinformation

• Name: Diethyl (1,3-Dithian-2-yl)phosphonate
• Synonyme: (1,3-Dithian-2-yl)phosphonic Acid Diethyl Ester
• Marke: Biosynth
• Beschreibung: Diethyl (1,3-Dithian-2-yl)phosphonate is a podophyllotoxin analog that has been shown to have enhanced antitumor activity against murine leukemia and L1210 murine leukemia. It is an ancillary in the asymmetric synthesis of β-amino acid derivatives, benzylidene acetals, and podophyllotoxin analogues. The l1210 murine leukemia cells are sensitive to diethyl (1,3-dithian-2-yl)phosphonate because it can form covalent bonds with DNA by electron donation. These compounds are also found to be cytotoxic against other tumor cells including human breast cancer cells.

Chemische Eigenschaften

• Molekulargewicht: 256.32 g/mol
• Formel: C₈H₁₇O₃PS₂
• Reinheit: Min. 95%
• Farbe/Form: Solid
• InChl: InChI=1S/C8H17O3PS2/c1-3-10-12(9,11-4-2)8-13-6-5-7-14-8/h8H,3-7H2,1-2H3
• InChI Key: InChIKey=BGXBJZCFBVTFFP-UHFFFAOYSA-N
• SMILES: CCOP(=O)(OCC)C1SCCCS1