4,7-Dimethyl-1,10-phenanthroline

CAS: 3248-05-3

Ref. 3D-FD60893

Produktinformation

• Name: 4,7-Dimethyl-1,10-phenanthroline
• Synonyme: 1,10-Phenanthroline, 4,7-dimethyl-, 1,8-Dimethyl-4,5-diazaphenanthrene, 4,7-Dimethy-1,10-Phenathroline, 4,7-Dimethyl-o-phenanthroline, Nsc 4281, Timtec-Bb Sbb008716

Beschreibung

4,7-Dimethyl-1,10-phenanthroline (DMPA) is a bifunctional molecule that can act as an electron transfer agent in the mitochondrial respiratory chain. DMPA has been shown to be cytotoxic and pro-apoptotic by inhibiting mitochondrial membrane potential and increasing oxidative stress. DMPA also has anti-cancer properties due to its ability to inhibit nuclear factor kappa-light-chain-enhancer of activated B cells (NFkB). The quinoid moiety of DMPA can undergo oxidation to form a radical cation that may be responsible for its toxicity. DMPA also interacts with hydrogen bonding groups on DNA and other biomolecules.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 208.26 g/mol
• Formel: C₁₄H₁₂N₂
• Reinheit: Min. 95%