Diloxanide furoate

CAS: 3736-81-0

Ref. 3D-FD63298

Produktinformation

• Name: Diloxanide furoate
• Synonyme: 2,2-Dichloroacetamideo-4-N-methylphenyl 2-furoate, 2-Furancarboxylic acid, 4-((dichloroacetyl)methylamino)phenyl ester, 2-Furancarboxylic acid, 4-[(2,2-dichloroacetyl)methylamino]phenyl ester, 2-Furoic acid, ester with 2,2-dichloro-4'-hydroxy-N-methylacetanilide, 4-((Dichloroacetyl)methylamino)phenyl 2-furoate, 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furancarboxylat, 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furancarboxylat [IUPAC], 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furoat, 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furoat [IUPAC], 4-(N-Methyl-2,2-dichloroacetamideo)phenyl 2-furoate, 4-Hydroxy-N-methyl dichloroacetanilide 2-furoate, 4-[(Dichloroacetyl)(Methyl)Amino]Phenyl Furan-2-Carboxylate, 8073 Cb, Acetanilide, 2,2-dichloro-4′-hydroxy-N-methyl-, 2-furoate (ester), Amebiazol, Cb 8073, Dichlofurazol, Diclofurazol, Diloxanid furoate, Entamide 2-furoate, Entamide furoate, Furamide, Furamide (amebicide), Furentomin, Furoic acid, ester with 2,2-dichloro-4′-hydroxy-N-methylacetanilide, Histomibal, Miforon, Unii-Yp4N72Iw34
• CAS: 3736-81-0

Beschreibung

Diloxanide furoate is a drug that belongs to the class of sulfa drugs. It is an amoebicidal agent that has been shown to be effective against Entamoeba histolytica, as well as other amoebae. Diloxanide furoate inhibits the enzyme polymerase chain reaction (PCR) in bacteria and eukaryotic cells, which prevents DNA replication and transcription. The mechanism of action for diloxanide furoate is similar to that of sulfonamides, with the exception that it does not inhibit dihydropteroate synthase like sulfonamides do. This drug also has minimal toxicity, which may be due to its low solubility in water and lack of absorption from the gastrointestinal tract.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 328.15 g/mol
• Formel: C₁₄H₁₁Cl₂NO₄
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3
• InChI Key: InChIKey=BDYYDXJSHYEDGB-UHFFFAOYSA-N
• SMILES: CN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1