5-Deoxy-5-Fluoroarbekacin

CAS: 119783-91-4

Ref. 3D-FD78045

Produktinformation

• Name: 5-Deoxy-5-Fluoroarbekacin
• Synonyme: (S)-O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl-(1-4))-N1-(4-amino-2-hydroxy-1-oxobutyl)-2,5-dideoxy-5-fluoro-D-streptamine, 5-Deoxy-5-epi-5-fluoro-arbekacin, D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl-(1-4))-N1-(4-amino-2-hydroxy-1-oxobutyl)-2,5-dideoxy-5-fluoro-, (S)-, (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)oxy]-3-fluorocyclohexyl}-2-hydroxybutanamide

Beschreibung

5-Deoxy-5-fluoroarbekacin is a quinolone antibiotic that has been shown to have an affinity for the 50S ribosomal subunit. It inhibits bacterial growth by binding to the 50S ribosomal subunit and inhibiting protein synthesis, leading to cell death. 5-Deoxy-5-fluoroarbekacin has been shown to bind to the 50S ribosomal subunit with a shift of 1.5 ppm and a conformational change of -0.8 ppm from its free form. The chemical shifts of 5-deoxy-5-fluoroarbekacin are in agreement with those observed for other antibiotics, such as chloramphenicol and erythromycin, which also bind to the 50S ribosomal subunit. The spectroscopic experiments show that 5-deoxy-5-fluoroarbekacin has no heteronuclear couplings and resonances, which

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 554.61 g/mol
• Formel: C₂₂H₄₃FN₆O₉
• Reinheit: Min. 95%