(2S)-4,4-Difluoropyrrolidine-2-carboxylic acid
CAS: 52683-81-5
Ref. 3D-FD98524
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Produktinformation
Name:
(2S)-4,4-Difluoropyrrolidine-2-carboxylic acid
Synonyme:
- L-Proline
- 4,4-difluoro- (9CI)
- Proline, 4,4-Difluoro-
- 4,4-Difluoro-pyrrolidine-2-carboxylic acid
- (2S)-4,4-difluoropyrrolidine-2-carboxylic acid
Beschreibung:
(2S)-4,4-Difluoropyrrolidine-2-carboxylic acid is a low potency μ-opioid receptor agonist. It is a neutral protonated molecule with a pKa of 6.8 and a hydrophobic effect. This drug has been shown to be effective in the treatment of cancer, as well as for pain relief in humans. (2S)-4,4-Difluoropyrrolidine-2-carboxylic acid binds to the human protein and selectively activates it without activating other receptors or ion channels. It has also been shown to activate signal transducer and activator of transcription 3 (STAT3). STAT3 activation prevents apoptosis by inhibiting the production of reactive oxygen species and stimulating DNA repair pathways.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
151.11 g/mol
Formel:
C5H7F2NO2
Reinheit:
Min. 95%
InChl:
InChI=1S/C5H7F2NO2/c6-5(7)1-3(4(9)10)8-2-5/h3,8H,1-2H2,(H,9,10)/t3-/m0/s1
InChI Key:
InChIKey=ZPBIYZHGBPBZCK-VKHMYHEASA-N
SMILES:
O=C(O)[C@@H]1CC(F)(F)CN1
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