1-(1,3-Dihydro-3-oxo-1-isobenzofuranyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione

CAS: 81820-68-0

Ref. 3D-FD99802

Produktinformation

• Name: 1-(1,3-Dihydro-3-oxo-1-isobenzofuranyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione
• Synonyme: 1-Phthalidyl-5-fluorouracil, 2,4(1H,3H)-pyrimidinedione, 1-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5-fluoro-, N₁-Phthalidyl-5-fluorouracil

Beschreibung

1-(1,3-Dihydro-3-oxo-1-isobenzofuranyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione is a fluoropyrimidine prodrug that is metabolized to 5-fluorouracil in the body. 1-(1,3-Dihydro-3-oxo-1-isobenzofuranyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione has been shown to be effective against cancer cells in vitro and in vivo. This drug binds to DNA at the O6 position of guanine and inhibits DNA synthesis. Clinical studies have shown that 1-(1,3-Dihydro-3-oxo-1-isobenzofuranyl)-5-fluoro--2,4(1H,3H)-pyrimidinedione is well

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 262.19 g/mol
• Formel: C₁₂H₇FN₂O₄
• Reinheit: Min. 95%
• InChl: InChI=1S/C12H7FN2O4/c13-8-5-15(12(18)14-9(8)16)10-6-3-1-2-4-7(6)11(17)19-10/h1-5,10H,(H,14,16,18)
• InChI Key: InChIKey=JADGCGSQDUSAED-UHFFFAOYSA-N
• SMILES: O=C1OC(n2cc(F)c(=O)[nH]c2=O)c2ccccc21