Ethyl 5-[4-(Difluoromethoxy)Phenyl]-3-Methyl-7-Oxo-8-Oxa-2-Azabicyclo[ 4.3.0]Nona-3,10-Diene-4-Carboxylate

CAS: 92638-14-7

Ref. 3D-FE102814

Produktinformation

• Name: Ethyl 5-[4-(Difluoromethoxy)Phenyl]-3-Methyl-7-Oxo-8-Oxa-2-Azabicyclo[ 4.3.0]Nona-3,10-Diene-4-Carboxylate
• Synonyme: Furo(3,4-b)pyridine-3-carboxylic acid, 4-(4-(difluoromethoxy)phenyl)-1,4,5,7-tetrahydro-2-methyl-5-oxo-, ethyl ester

Beschreibung

Ethyl 5-[4-(difluoromethoxy)phenyl]-3-methyl-7-oxo-8-oxa-2-azabicyclo[4.3.0]nona-3,10-diene-4carboxylate (EFD) is a synthetic compound that interacts with calcium channels in the muscle cell membrane and modulates the flow of calcium ions through the channel. This interaction leads to an increase in intracellular calcium concentrations, which can activate protein kinase C and modify ion transport system function. EFD has been shown to be effective against neuroblastoma cells, as well as reticulum and sarcoplasmic reticulum cells. It also has an antagonistic effect on the ryanodine receptors in these cells, leading to increased release of calcium from storage sites within the cell.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 365.33 g/mol
• Formel: C₁₈H₁₇F₂NO₅
• Reinheit: Min. 95%
• InChl: InChI=1S/C18H17F2NO5/c1-3-24-16(22)13-9(2)21-12-8-25-17(23)15(12)14(13)10-4-6-11(7-5-10)26-18(19)20/h4-7,14,18,21H,3,8H2,1-2H3
• InChI Key: InChIKey=DHQLGUXVYWAZOP-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(C)NC2=C(C(=O)OC2)C1c1ccc(OC(F)F)cc1