2-Ethyl-6-hydroxypyrimidin-4(3H)-one
CAS: 3709-98-6
Ref. 3D-FE123957
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Produktinformation
Name:
2-Ethyl-6-hydroxypyrimidin-4(3H)-one
Synonyme:
- 4(3H)-pyrimidinone
- 2-ethyl-6-hydroxy-
- 2-Ethylpyrimidine-4,6-diol
- 4,6-Pyrimidinediol, 2-Ethyl-
Beschreibung:
2-Ethyl-6-hydroxypyrimidin-4(3H)-one is an intermediate in the synthesis of the drug propionamide. It can be prepared by reacting ethyl pyrimidine-2,4(1H,3H)-dione with diethyl chloroacetate in the presence of a catalyst such as sodium methoxide. The reaction time can vary from one to three hours and the optimal reaction temperature is between 50°C and 60°C. 2-Ethyl-6-hydroxypyrimidin-4(3H)-one can also be prepared using propionitrile and alkali solution. This process takes approximately four hours to complete, but yields a greater quantity of product than when using diethyl chloroacetate.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
140.14 g/mol
Formel:
C6H8N2O2
Reinheit:
Min. 95%
InChl:
InChI=1S/C6H8N2O2/c1-2-4-7-5(9)3-6(10)8-4/h3H,2H2,1H3,(H2,7,8,9,10)
InChI Key:
InChIKey=CBXPKEZRCKCOID-UHFFFAOYSA-N
SMILES:
CCc1nc(O)cc(=O)[nH]1
MDL:
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