Produktinformation
Name:
Elvucitabine
Synonyme:
- 4-Amino-1-[(2S,5R)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-2(1H)-pyrimidinoneACH 126443L-Fd 4C
- 2(1H)-Pyrimidinone, 4-amino-1-[(2S,5R)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-
- 2(1H)-Pyrimidinone, 4-amino-1-[2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-, (2S-cis)-
- 4-Amino-1-[(2S,5R)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-2(1H)-pyrimidinone
- 4-amino-5-fluoro-1-[(2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2(1H)-one
- <span class="text-smallcaps">L</span>-Fd 4C
- Ach 126443
- Beta-<span class="text-smallcaps">L</span>-Fd4C
- L-Fd 4C
Beschreibung:
Elvucitabine is a nucleoside analog that inhibits the replication of HIV-1. It is active against HIV-1 isolates resistant to other antiviral drugs, such as zidovudine. Elvucitabine is a prodrug that is metabolized by liver enzymes to its active form, cytidine monophosphate (CMP). This drug has shown antiviral potency in vitro and in vivo against HIV-1. The pharmacokinetic properties of elvucitabine are similar to those of other nucleoside analogs, with an elimination rate of about 70%. This drug also has potential for use in treatment of hepatitis B and C. Elvucitabine has been shown to have biochemical research applications in cancer treatment and the study of growth factors.
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Marke:
Biosynth
Langzeitlagerung:
Hinweise:
Chemische Eigenschaften
Molekulargewicht:
227.19 g/mol
Formel:
C9H10FN3O3
Reinheit:
Min. 95%
InChl:
InChI=1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m1/s1
InChI Key:
InChIKey=HSBKFSPNDWWPSL-VDTYLAMSSA-N
SMILES:
Nc1nc(=O)n([C@@H]2C=C[C@H](CO)O2)cc1F
MDL:
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Flammpunkt:
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