2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride

CAS: 875756-97-1

Ref. 3D-FE36315

Produktinformation

• Name: 2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride
• Synonyme: Hoechst 33342 trihydrochloride

Beschreibung

2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride (EPMB) is a DNA binding agent that is used in tumor detection and research into apoptosis. It has been shown to inhibit the activity of p-glycoprotein, which is an efflux pump protein, and Bcl-2 protein. EPMB has also been shown to cause apoptosis in human squamous cell carcinoma cells in a concentration dependent manner. This compound has shown potential as a treatment for cancer because it inhibits the ability of cancer cells to proliferate by binding to the NMDA receptor.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 561.93 g/mol
• Formel: C₂₇H₂₈N₆O·3HCl·xH₂O
• Reinheit: Min. 95%
• Farbe/Form: Yellow Powder