Ethyl 3-oxo-4-phenylbutanoate

CAS: 718-08-1

Ref. 3D-FE46407

Produktinformation

• Name: Ethyl 3-oxo-4-phenylbutanoate
• Synonyme: Benzenebutanoic Acid, Beta-Oxo-, Ethyl Ester, 3-Oxo-4-Phenyl-Butyric Acid Ethyl Ester

Beschreibung

Ethyl 3-oxo-4-phenylbutanoate is an impurity of the drug 4-nitrophenylacetic acid, which is used in the synthesis of the anti-cancer drug oxaliplatin. This chemical is a marker for the presence of 4-nitrophenylacetic acid and can be detected by gas chromatography. The profile of this compound includes impurities such as 2,5-dimethoxybenzoic acid and 2,5-diketopiperazine. Epidemiological studies have shown that this impurity is a potential risk factor for breast cancer. Basic hydrolysis of ethyl 3-oxo-4-phenylbutanoate has been shown to generate chloride ions and oxobutanoate ions. Chlorine ions are toxic to humans and animals and can cause respiratory irritation, nausea, vomiting, diarrhoea, convulsions, and death at high doses. Oxobutanoate ions

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 206.24 g/mol
• Formel: C₁₂H₁₄O₃
• Reinheit: Min. 95%