Ethyl 4-(2-chloroacetylamino)benzoate

CAS: 26226-72-2

Ref. 3D-FE54252

Produktinformation

• Name: Ethyl 4-(2-chloroacetylamino)benzoate
• Synonyme: 4-(2-Chloro-acetylamino)-benzoic acid ethyl ester, Ethyl 4-[(Chloroacetyl)Amino]Benzoate

Beschreibung

Ethyl 4-(2-chloroacetylamino)benzoate is a reagent that is used to produce aminosulfonyl chlorides. It can be used as an efficient method for the deacylation of thionylated peptides and proteins. The reaction product, which is a sulfonamide, can be hydrolyzed by acid to give the corresponding carboxylic acid. This reagent also has been shown to inhibit the activity of cytosolic phospholipase A2 in human erythrocytes and has been used as a probe for this enzyme in other systems. The inhibition of this enzyme leads to a decrease in arachidonic acid production, which may have therapeutic potential in diseases such as atherosclerosis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 241.67 g/mol
• Formel: C₁₁H₁₂ClNO₃
• Reinheit: Min. 95%
• InChl: InChI=1S/C11H12ClNO3/c1-2-16-11(15)8-3-5-9(6-4-8)13-10(14)7-12/h3-6H,2,7H2,1H3,(H,13,14)
• InChI Key: InChIKey=ZVRJEYAQESBSSH-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1ccc(NC(=O)CCl)cc1