Endomorphin-2

CAS: 141801-26-5

Ref. 3D-FE73364

Produktinformation

• Name: Endomorphin-2
• Synonyme: Endomorphin-2 (Human, Bovine), Ypff-Nh2, Tyr-Pro-Phe-Phe-Nh2, (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]-2-phenyl-ethyl]pyrrolidine-2-carboxamide, L-tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide
• CAS: 141801-26-5

Beschreibung

Endomorphin-2 is a cyclic peptide that has been shown to have analgesic and anti-inflammatory effects. It binds to the kappa-opioid receptor and inhibits locomotion in mice. It also has shown to be effective at treating bowel disease in vivo models. The biological properties of endomorphin-2 include its ability to stimulate the release of neurokinin-1 from trigeminal nerve endings, which then stimulates the release of substance P from sensory neurons. Endomorphin-2 does not bind to receptors for endomorphin 1 or endomorphin 3, but it does bind with high affinity to the neurokinin-1 receptor.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 571.67 g/mol
• Formel: C₃₂H₃₇N₅O₅
• Reinheit: Min. 95%