Ebselen

CAS: 60940-34-3

Ref. 3D-FE75162

Produktinformation

• Name: Ebselen
• Synonyme: 1,2-Benzisoselenazol-3(2H)-one, 2-phenyl-, 2-Phenyl-1,2-benzisoselenazol-3(2H)-one, 2-Phenyl-1,2-benzoisoselenazol-3(2H)-one, 2-Phenyl-1,2-benzoselenazol-3-one, 2-Phenylbenzo[d][1,2]selenazol-3(2H)-one, 2-phenyl-1,2-benzoselenazol-3(2H)-one, Ccg-39161, Dr 3305, Lopac E 3520, NSC 639762, Pz 51, Spi 1005

Beschreibung

Ebselen is a non-toxic organoselenium compound with antioxidant, anti-inflammatory and cytoprotective properties. Ebselen is an inhibitor of lipoxygenases, nitric oxide (NO) synthases, protein kinase C, H+/K+-ATPase, thioredoxin reductase and NADPH oxidase. Recently, ebselen has been identified by several studies as a covalent inhibitor of the main protease Mpro from coronaviruses. For the SARS-CoV-2 main protease Mpro, the IC50 value is 0.67 μM and EC50 is 4.57 μM.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 274.18 g/mol
• Formel: C₁₃H₉NOSe
• Reinheit: Min. 98 Area-%
• Farbe/Form: Powder
• InChl: InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
• InChI Key: InChIKey=DYEFUKCXAQOFHX-UHFFFAOYSA-N
• SMILES: O=c1c2ccccc2[se]n1-c1ccccc1