5-[4-Fluoro-1-[(6-methyl-2-pyridinyl)acetyl]-2,3-dihydro-1H-indol-5-yl]-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAS: 1337532-29-2

Ref. 3D-FF103212

Produktinformation

• Name: 5-[4-Fluoro-1-[(6-methyl-2-pyridinyl)acetyl]-2,3-dihydro-1H-indol-5-yl]-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• CAS: 1337532-29-2

Beschreibung

5-[4-Fluoro-1-[(6-methyl-2-pyridinyl)acetyl]-2,3-dihydro-1H-indol-5-yl]-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a melatonin analog that is under development for the treatment of human osteosarcoma cells. Melatonin has been shown to induce apoptosis in human osteosarcoma cells by activating proapoptotic proteins and inhibiting autophagy. 5-[4-Fluoro-1-[(6 methyl 2 pyridinyl)acetyl]-2,3 dihydro 1H indol 5 yl]-7 methyl 7 H pyrrolo [2, 3 d] pyrimidin 4 amine also inhibits proliferation of human malignant cells and induces cell lysis in blood disorders such as myelod

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 416.45 g/mol
• Formel: C₂₃H₂₁FN₆O
• Reinheit: Min. 95%
• InChl: InChI=1S/C23H21FN6O/c1-13-4-3-5-14(28-13)10-19(31)30-9-8-16-18(30)7-6-15(21(16)24)17-11-29(2)23-20(17)22(25)26-12-27-23/h3-7,11-12H,8-10H2,1-2H3,(H2,25,26,27)
• InChI Key: InChIKey=PRWSIEBRGXYXAJ-UHFFFAOYSA-N
• SMILES: Cc1cccc(CC(=O)N2CCc3c2ccc(-c2cn(C)c4ncnc(N)c24)c3F)n1