Fmoc-Phe-Ser(tBu)-OH

CAS: 157675-78-0

Ref. 3D-FF111292

Produktinformation

• Name: Fmoc-Phe-Ser(tBu)-OH
• Marke: Biosynth
• Beschreibung: Fmoc-Phe-Ser(tBu)-OH is a pentafluorophenyl ester of the amino acid phenylalanine. It is used in solid-phase peptide synthesis to link amines and carboxylic acids. Fmoc-Phe-Ser(tBu)-OH is used as an intermediate in the synthesis of peptides with a C-terminal amidated or methyl esters. The coupling reaction is catalyzed by 1-hydroxybenzotriazole (HOBT) and N,N'-dicyclohexylcarbodiimide (DCC). HOBT reacts with the hydroxyl group on the β carbon of the ester to form an acetoxy group, which reacts with the amine on the opposite side of the peptide chain to form a new amide bond. DCC reacts with both reactive groups, forming an iminoester intermediate. This intermediate can be hydroly

Chemische Eigenschaften

• Molekulargewicht: 530.61 g/mol
• Formel: C₃₁H₃₄N₂O₆
• Reinheit: Min. 95%
• InChl: InChI=1S/C31H34N2O6/c1-31(2,3)39-19-27(29(35)36)32-28(34)26(17-20-11-5-4-6-12-20)33-30(37)38-18-25-23-15-9-7-13-21(23)22-14-8-10-16-24(22)25/h4-16,25-27H,17-19H2,1-3H3,(H,32,34)(H,33,37)(H,35,36)/t26-,27-/m0/s1
• InChI Key: InChIKey=INUVWIJXMJVBLO-SVBPBHIXSA-N
• SMILES: CC(C)(C)OC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O