Fazarabine

CAS: 65886-71-7

Ref. 3D-FF157115

Produktinformation

• Name: Fazarabine
• Synonyme: 1,3,5-Triazin-2(1H)-one, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-, 1,3,5-triazin-2(1H)-one, 4-amino-1-beta-D-arabinofuranosyl-, 1-.beta.-D-Arabinofuranosyl-5-azacytosine, 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-5-azacytosine, 1b-D-Arabinofuranosyl-5-azacytosine, 4-Amino-1-(beta-D-arabinofuranosyl)-1,3,5-triazin-2(1H)-one, 4-Amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-1,3,5-triazin-2(1H)-one, 4-Amino-1b-D-arabinofuranosyl-s-triazin-2(1H)-one, 5-Aza-1-arabinosylcytosine, 5-Azacytosine arabinoside, 65886-71-7, Kymarabine, NSC 281272, ara-AC, 1,3,5-Triazin-2(1H)-one, 4-amino-1-β-D-arabinofuranosyl-, 4-Amino-1-β-D-arabinofuranosyl-1,3,5-triazin-2(1H)-one, 1-β-D-Arabinofuranosyl-5-azacytosine

Beschreibung

Fazarabine is a nucleoside analog that has been shown to be a potent inhibitor of the enzyme fyn tyrosine kinase and to have cytotoxic effects on human leukemia HL-60 cells. The chemical stability of fazarabine has been demonstrated in methyltransferase inhibition studies. Fazarabine is also an anti-cancer compound with selective toxicity towards colorectal adenocarcinoma cells. Fazarabine inhibits cell proliferation by inhibiting protein synthesis, which may be due to its ability to act as a DNA template, or its receptor activity. Fazarabine also has immunosuppressive properties and can be used for the treatment of autoimmune diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 244.2 g/mol
• Formel: C₈H₁₂N₄O₅
• Reinheit: Min. 95%