Fexofenadine

CAS: 83799-24-0

Ref. 3D-FF23281

Produktinformation

• Name: Fexofenadine
• Synonyme: 2-(4-[1-Hydroxy-4-[4-(hydroxy-diphenyl-methyl)-piperidin-1-yl]-butyl]-phenyl)-2-methyl-propionic acid, 2-(4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]phenyl)-2-methylpropanoic acid, 2-[4-(1-Hydroxy-4-{4-[Hydroxy(Diphenyl)Methyl]Piperidin-1-Yl}Butyl)Phenyl]-2-Methylpropanoic Acid, 4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethylbenzeneacetic acid, 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylphenylacetic acid, Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, Carboxyterfenadine, Fexet, Mdl 16455, Telfast 120, Terfenadine acid metabolite, Terfenadine carboxylate, Terfenidine Carboxylate

Beschreibung

Fexofenadine is a selective histamine H1 receptor antagonist that has been shown to be effective in the treatment of allergic rhinitis. It is well tolerated and does not have any significant drug interactions. Fexofenadine is metabolized by cytochrome P450 (CYP) enzymes and undergoes extensive first-pass metabolism. This means that it should not interact with CYP inhibitors such as ketoconazole or cimetidine, but may increase the effects of CYP inducers such as phenobarbital or rifampin. Fexofenadine has been shown to inhibit the activity of human multidrug resistance protein 1 (MDR1) and P-glycoprotein (P-gp).

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 501.66 g/mol
• Reinheit: Min. 95 Area-%
• Farbe/Form: White Off-White Powder