4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic acid methyl ester

CAS: 121659-86-7

Ref. 3D-FF23458

Produktinformation

• Name: 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic acid methyl ester
• Synonyme: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic acid methyl esterMethyl 2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxyl ate, 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxylic acid methyl ester, 3-Quinolinecarboxylic acid, 2-cyclopropyl-4-(4-fluorophenyl)-, methyl ester, Methyl 2-Cyclopropyl-4-(4-Fluorophenyl)Quinoline-3-Carboxylate, Methyl 2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate

Beschreibung

4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic acid methyl ester (CPCQ) is a hmg coa reductase inhibitor that is used in the evaluation of enzyme inhibition. CPCQ has been shown to inhibit hmg coa reductase and other enzymes, such as phosphatidylcholine acyltransferase, with IC50 values in the low micromolar range. This drug has shown no significant toxic effects on cells or animals at doses up to 200 mg/kg. The photophysical properties of this compound are fluorescence and active methylene emission, which is exhibited by its quinolinecarboxylic acid moiety.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 321.34 g/mol
• Formel: C₂₀H₁₆FNO₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C20H16FNO2/c1-24-20(23)18-17(12-8-10-14(21)11-9-12)15-4-2-3-5-16(15)22-19(18)13-6-7-13/h2-5,8-11,13H,6-7H2,1H3
• InChI Key: InChIKey=RNXQZVFWKIPEOJ-UHFFFAOYSA-N
• SMILES: COC(=O)c1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1